18
Sep
09

Resveratrol

Or

What Spam Comments Help Us Discover

So I found this comment which certainly appears to be spam:

Oh, Good post.so gald to see your views about resveratrol.I’m also looking for resveratrol supplements. I found a lots of websites online.
and i have read some other idea about resveratrol-anti-aging: , are they true or not?
Anyway, I’ll try resveratrol soon.

I’m almost certain it’s spam, because it was posted here and I have no mention of resveratrol on that page. The person’s link was similarly dubious as it links to “Dr Oz Resveratrol Review.” For this reason, it will remain in the spam dungeon along with all of the other spam-like comments.

What is resveratrol? Well, it’s a chemical produced by plants when they are nutrient starved. The red varieties of grapes (merlot and cabernet sauvignon have some of the highest levels) have quite a high concentration relative to many other varieties and it was speculated that this may be partially responsible for the so-called “French paradox.” It has some evidence-based support of lifespan increasing claims when dealing with high doses given to nematodes, fruit flies, and yeast. This evidence, however, is compensated for by the complete refutation that it has the same effects in mice; it does not. The only time resveratrol had an effect on longevity was when it was already decreased by high-fat diets. It doesn’t increase lifespan, it prevents some genes expressed which may play a role in reducing lifespan from high fat. Namely, blood glucose levels of high-fat diet mice were similar to that of normal diet mice although fatty acid and cholesterol levels were still elevated relative to normal diet mice.

For any type of cancer prevention, doses must extremely high to overcome the low bioavailability of resveratrol. To get the needed dosages which were present in these studies, doses would range between 1.7 kg to 32 kg PER DAY. That’s right, at least more than 2 lbs of pure resveratrol. I certainly think a direct manipulation of the genome would be far cheaper and probably more effective. It won’t result in any of the beneficial claims made by these websites because the levels necessary for these effects cannot possibly be reached.

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1 Response to “Resveratrol”


  1. September 19, 2009 at 10:52 pm

    After I posted my last thing on the future, I got 6 comments just like that one in my spam. Three were from the same guy, on different posts of mine. The last post was tagged for health care and health reform, and the spam took you to suspicious health reform sites. Or pharma stuff, as pharma was also tagged. They got people making a living doing spam!


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