06
Feb
10

Ongoing list of things I read today…

If you find something I should read; leave a link in the comments!

So far, I’ve finished the following-with comments

Scientist wants to grow giant squid

Could be interesting…

Feathers at a Fine Scale, Shawkey et al.

Because I wanted to see how much was actually known about structural-based coloration in birds.

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor

A quote:

β-TrCP is an E3 ligase that targets various substrates essential for many aspects of tumorigenesis.

Here we show that β-TrCP depletion suppresses prostate cancer and identify a relevant growth control mechanism. shRNA targeted against β-TrCP reduced prostate cancer cell growth and cooperated with androgen ablation in vitro and in vivo. We found that β-TrCP inhibition leads to upregulation of the aryl hydrocarbon receptor (AhR) mediating the therapeutic effect. This phenomenon could be ligand independent, as the AhR ligand 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) did not alter prostate cancer cell growth. We detected high AhR expression and activation in basal cells and atrophic epithelial cells of human cancer bearing prostates. AhR expression and activation is also significantly higher in tumor cells compared to benign glandular epithelium.

Genetic and Environmental Influences on self-reported G-Spots in Women

Because self-reporting on matters of anatomy is actually a good way to measure something… It would be almost identical to ask “how many different tastes to you experience?” and expect that self-reporting to tell me how many types of chemoreceptors are present on the tongue. (most of our “taste” comes from our nasal chemoreceptors)

The Moon May Have Been Created By a Massive Nuclear Blast Inside the Earth

Parsimonious explanation: FAIL

The HIGHLY reactive types of uranium (which would go “Boom!” rather than fizzle) are produced by either fission or decay of U-238. They are also LIGHTER in weight than U-238, so if a the earth was completely molten, and spinning fast enough to force heavier materials to the equator in higher concentrations (this would be VERY fast), it would mean that U-238 would be concentrated in a band around the equator; such a band does not exist however you would try to re-arrange the planet; even extrapolating the early shape of the Earth. Assuming it wouldn’t go critical before such a huge mass would exist so as to blow 1% of the Earth into orbit. Natural nuclear reactions are actually fairly well explored and explosive forces associated with nuclear weapons require a rapid increase to supercriticality. The formation of such large natural nuclear bombs would occur slowly (unless the Earth were spinning so fast as to tear itself apart) and this slow build up would cause the deposit to become critical, “burn off” some of the nuclear material, and return back to subcriticality. Natural nuclear bombs are not possible given Earth-like conditions. The reason natural nuclear reactors actually existed is probably due to water dissolving and depositing rich seams of Uranium oxide which was (at the time these reactors formed) more fortified with U-235 than at present owing to it’s short half-life. Note how these natural reactors formed by the action of water didn’t become run-away explosives.

CITES backs bluefin tuna ban to be decided next month

This could make me a very unhappy person, if I hadn’t already read this.

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